| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD196/CCR6 |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | P51684 |
| 背景信息 | C-C chemokine receptor type 6 (CD196/CCR6) is a ~42 kDa protein. Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins. Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels. Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity. 1. Baba, M. et al. (1997) The Journal of biological chemistry 272, 14893-8. PMID: 9169459 2. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 3. Lee, AY. et al. (2015) Cytokine 72, 97-101. PMID: 25585877 4. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 5. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 6. Caballero-Campo, P. et al. (2014) Journal of cellular physiology 229, 68-78. PMID: 23765988 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
| 产品名称 | 点击数 |
|---|---|
| 炔诺酮单抗 | 5673 |
| 磺胺氯吡嗪单抗 | 5677 |
| 呋喃苯烯酸钠单抗 | 5546 |
| 呋喃它酮代谢物(2-NPAMOZ)单抗 | 5524 |
| 呋喃西林代谢物(2-NPSEM)单抗 | 5376 |
| 磺胺喹恶啉单抗 | 5582 |
| 苯丙酸诺龙单抗 | 5500 |
| 司帕沙星单抗 | 5333 |
| 妥布霉素单抗 | 5562 |
| 甲氧氯普胺单抗 | 5446 |
| 莫能菌素单抗 | 5538 |
| 多粘菌素B(粘菌素)单抗 | 5866 |
| 磺胺类单抗 | 5699 |
| 托灭酸(托芬那酸)单抗 | 5452 |
| 卡洛芬单抗 | 5381 |
| 喹乙醇代谢物MQCA单抗 | 5555 |
| 氟尼辛单抗 | 5478 |
| 磺胺二甲嘧啶(SM2)单抗 | 5300 |
| 诺龙(19-去甲睾酮)单抗 | 5392 |
| 阿苯达唑-2-氨基砜单抗 | 5368 |