当前位置：首页>产品中心>单抗/多抗>HEK293T Human CD196/CCR6 Stable Cell Line|HEK293T人CD196/CCR6稳定细胞系(靶标：人CD196/CCR6稳定表达细胞系)
HEK293T Human CD196/CCR6 Stable Cell Line|HEK293T人CD196/CCR6稳定细胞系(靶标：人CD196/CCR6稳定表达细胞系)
- 货号：RB9THW383818
- 价格：面议
- 点击：306
产品介绍
产品参数
| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD196/CCR6 |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | P51684 |
| 背景信息 | C-C chemokine receptor type 6 (CD196/CCR6) is a ~42 kDa protein. Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins. Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels. Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity. 1. Baba, M. et al. (1997) The Journal of biological chemistry 272, 14893-8. PMID: 9169459 2. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 3. Lee, AY. et al. (2015) Cytokine 72, 97-101. PMID: 25585877 4. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 5. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 6. Caballero-Campo, P. et al. (2014) Journal of cellular physiology 229, 68-78. PMID: 23765988 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
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