| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD196/CCR6 |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | P51684 |
| 背景信息 | C-C chemokine receptor type 6 (CD196/CCR6) is a ~42 kDa protein. Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins. Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels. Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity. 1. Baba, M. et al. (1997) The Journal of biological chemistry 272, 14893-8. PMID: 9169459 2. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 3. Lee, AY. et al. (2015) Cytokine 72, 97-101. PMID: 25585877 4. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 5. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 6. Caballero-Campo, P. et al. (2014) Journal of cellular physiology 229, 68-78. PMID: 23765988 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7494 |
| 人触珠蛋白单克隆抗体 | 7679 |
| 贾第鞭毛虫单克隆抗体 | 7348 |
| 阿米巴单克隆抗体 | 7852 |
| 胃蛋白酶单克隆抗体 | 7374 |
| 胃蛋白酶原II单克隆抗体 | 7561 |
| 胃蛋白酶原I单克隆抗体 | 7295 |
| 艰难梭菌毒素A单克隆抗体 | 7443 |
| 艰难梭菌毒素B单克隆抗体 | 7734 |
| 艰难梭菌GDH单克隆抗体 | 7744 |
| 诺如病毒单克隆抗体 | 7233 |
| 伤寒沙门氏菌单克隆抗体 | 7310 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6834 |
| 幽门螺杆菌单克隆抗体 | 7348 |
| 钙卫蛋白单克隆抗体 | 7134 |
| 乳铁蛋白单克隆抗体 | 7469 |
| 转铁蛋白单克隆抗体 | 7471 |
| 血红蛋白单克隆抗体 | 7204 |
| 腺病毒单克隆抗体 | 7418 |
| 轮状病毒单克隆抗体 | 7792 |