| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD196/CCR6 |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | P51684 |
| 背景信息 | C-C chemokine receptor type 6 (CD196/CCR6) is a ~42 kDa protein. Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins. Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels. Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity. 1. Baba, M. et al. (1997) The Journal of biological chemistry 272, 14893-8. PMID: 9169459 2. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 3. Lee, AY. et al. (2015) Cytokine 72, 97-101. PMID: 25585877 4. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 5. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 6. Caballero-Campo, P. et al. (2014) Journal of cellular physiology 229, 68-78. PMID: 23765988 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 7535 |
| 白细胞介素6(IL-6)单克隆抗体 | 7247 |
| 肝素结合蛋白单克隆抗体 | 6672 |
| CRP单克隆抗体 | 7459 |
| 猫胰脂肪酶单克隆抗体 | 7081 |
| 马SAA单克隆抗体 | 7373 |
| 犬腺病毒单克隆抗体 | 6833 |
| 犬轮状病毒单克隆抗体 | 6886 |
| 犬血红蛋白单克隆抗体 | 7801 |
| 犬胰脂肪酶单克隆抗体 | 6706 |
| 犬松弛素单克隆抗体 | 7048 |
| 犬冠状病毒单克隆抗体 | 7099 |
| 犬瘟病毒单克隆抗体 | 6787 |
| 犬细小病毒单克隆抗体 | 7211 |
| 猫瘟病毒单克隆抗体 | 7313 |
| 猫疱疹病毒单克隆抗体 | 7111 |
| 猫杯状病毒单克隆抗体 | 7513 |
| 猫SAA单克隆抗体 | 7178 |
| 犬CRP单克隆抗体 | 7695 |
| 犬、猫IgG单克隆抗体 | 7060 |