| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD196/CCR6 |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | P51684 |
| 背景信息 | C-C chemokine receptor type 6 (CD196/CCR6) is a ~42 kDa protein. Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins. Binds to defensin DEFB1 leading to increase in intracellular calcium ions and cAMP levels. Its binding to DEFB1 is essential for the function of DEFB1 in regulating sperm motility and bactericidal activity. 1. Baba, M. et al. (1997) The Journal of biological chemistry 272, 14893-8. PMID: 9169459 2. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 3. Lee, AY. et al. (2015) Cytokine 72, 97-101. PMID: 25585877 4. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 5. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 6. Caballero-Campo, P. et al. (2014) Journal of cellular physiology 229, 68-78. PMID: 23765988 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6292 |
| 多菌灵/阿苯达唑二合一单抗 | 6358 |
| 三氯噻嗪单抗 | 6457 |
| 吡唑醚菌酯单抗 | 6668 |
| 烯酰吗啉单抗 | 6481 |
| 抑霉唑单抗 | 6214 |
| 恶醚唑(苯醚甲环唑)单抗 | 6387 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6410 |
| 辛硫磷单抗 | 6470 |
| 多效唑单抗 | 6350 |
| 对硫磷单抗 | 6547 |
| 丙溴磷单抗 | 6585 |
| 戊唑醇单抗 | 6587 |
| 莠去津单抗 | 6465 |
| 灭蝇胺单抗 | 6154 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6453 |
| 2.4-二氯苯氧乙酸单抗 | 6295 |
| 甲基对硫磷单抗 | 6372 |
| 左旋咪唑单抗 | 6304 |
| 三唑磷单抗 | 6376 |