当前位置:首页>产品中心>单抗/多抗>HEK293T Human CD158k/KIR3DL2 Stable Cell Line|HEK293T人CD158k/KIR3DL2稳定细胞系(靶标:人CD158k/KIR3DL2稳定表达细胞系)

HEK293T Human CD158k/KIR3DL2 Stable Cell Line|HEK293T人CD158k/KIR3DL2稳定细胞系(靶标:人CD158k/KIR3DL2稳定表达细胞系)

  • 货号:RB9THW633818
  • 价格:面议
  • 点击:356
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产品介绍

产品参数

宿主种属HEK293T
应用FCM
靶标CD158k/KIR3DL2
稳定性和储存Frozen in liquid nitrogen.
登录号P43630
背景信息

Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.

1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270
2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952
3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464
产品特性Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
种属Human
【仅供科学研究使用】

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