当前位置:首页>产品中心>单抗/多抗>HEK293T Human CD10/MME Stable Cell Line|HEK293T人CD10/MME稳定细胞系(靶标:人CD10/MME稳定表达细胞系)

HEK293T Human CD10/MME Stable Cell Line|HEK293T人CD10/MME稳定细胞系(靶标:人CD10/MME稳定表达细胞系)

  • 货号:RB9THY401818
  • 价格:面议
  • 点击:395
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产品介绍

产品参数

宿主种属HEK293T
应用FCM
靶标CD10/MME
稳定性和储存Frozen in liquid nitrogen.
登录号P08473
背景信息

Neprilysin (CD10/MME) is a ~85 kDa protein. Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)).

1. Rice, GI. et al. (2004) The Biochemical journal 383, 45-51. PMID: 15283675
2. Skidgel, RA. et al. (1984) Peptides 5, 769-76. PMID: 6208535
3. Gafford, JT. et al. (1983) Biochemistry 22, 3265-71. PMID: 6349683
4. Le Moual, H. et al. (1994) European journal of biochemistry 221, 475-80. PMID: 8168535
5. Wisner, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 17979-84. PMID: 17101991
6. Brandt, I. et al. (2006) Clinical chemistry 52, 82-7. PMID: 16254193
产品特性Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
种属Human
【仅供科学研究使用】

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