Anti-TIMM23 Polyclonal Antibody|抗TIMM23多克隆抗体(靶标：线粒体内膜转位酶23)

形态	Liquid
宿主种属	Rabbit
克隆性	Polyclonal
抗体亚型	IgG
纯化方式	Purified by antigen affinity column.
内毒素水平	Please contact with the lab for this information.
应用	ELISA, IHC, WB
种属反应性	Human, Rat, Mouse
靶标	Mitochondrial import inner membrane translocase subunit Tim23, TIM23, TIMM23
免疫原	E. coli - derived recombinant TIMM23 (Glu2-Arg72).
储存缓冲液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和储存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
产品使用说明	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号	O14925, O35093, Q9WTQ8, Q5SRD1
背景信息	Mitochondrial import inner membrane translocase subunit Tim23 is a ~21 kDa protein. Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization. 1. Bauer, MF. et al. (1999) Journal of molecular biology 289, 69-82. PMID: 10339406 2. Akabane, S. et al. (2023) Cell reports 42, 112454. PMID: 37160114
备注	For research use only

【仅供科学研究使用】

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