当前位置:首页>产品中心>单抗/多抗>Anti-TIMM23 Polyclonal Antibody|抗TIMM23多克隆抗体(靶标:线粒体内膜转位酶23)

Anti-TIMM23 Polyclonal Antibody|抗TIMM23多克隆抗体(靶标:线粒体内膜转位酶23)

  • 货号:RB9THC876014
  • 价格:面议
  • 点击:418
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Rat, Mouse
靶标Mitochondrial import inner membrane translocase subunit Tim23, TIM23, TIMM23
免疫原E. coli - derived recombinant TIMM23 (Glu2-Arg72).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O14925, O35093, Q9WTQ8, Q5SRD1
背景信息

Mitochondrial import inner membrane translocase subunit Tim23 is a ~21 kDa protein. Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization.

1. Bauer, MF. et al. (1999) Journal of molecular biology 289, 69-82. PMID: 10339406
2. Akabane, S. et al. (2023) Cell reports 42, 112454. PMID: 37160114
备注For research use only
【仅供科学研究使用】

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