Anti-Mouse MPO Polyclonal Antibody|抗小鼠MPO多克隆抗体(靶标：小鼠髓过氧化物酶)
- 货号：RB9TMY413014
- 价格：面议
- 点击：534
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | EC:1.11.2.2, MPO, Mpo, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain |
| 免疫原 | E. coli - derived recombinant Mouse MPO (Ser289-Thr718). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P11247 |
| 背景信息 | Myeloperoxidase (MPO) is a ~81 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low density lipoprotein particles and limits vascular damage. 1. Gaut, JP. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 11961-6. PMID: 11593004 |
| 备注 | For research use only |
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