Anti-Human CD71/TFRC Recombinant Antibody|抗人CD71/TFRC重组抗体(靶标：人转铁蛋白受体1/CD71)
- 货号：RB9THY036053
- 价格：面议
- 点击：264
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, neutralization |
| 种属反应性 | Human |
| 靶标 | CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P02786 |
| 背景信息 | Transferrin receptor protein 1 (TRFC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. 1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738 2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5876 |
| 西马特罗单抗 | 5889 |
| 孕酮单抗 | 6052 |
| 氯霉素（CAP）单抗 | 5968 |
| 红霉素单抗 | 6011 |
| 地克珠利单抗 | 5721 |
| 无色孔雀石绿（LMG）单抗 | 5948 |
| 雌二醇单抗 | 5609 |
| 孔雀石绿（MG）单抗 | 6091 |
| 双酚A单抗 | 5887 |
| 呋喃妥因代谢物（2-NPAHD）单抗 | 5757 |
| 己烯雌酚单抗 | 5803 |
| 莱克多巴胺（RAC）单抗 | 5950 |
| 林可霉素单抗 | 6279 |
| 抗青霉素受体单抗 | 5736 |
| 大观霉素单抗 | 5815 |
| 克伦特罗（CL）单抗 | 6037 |
| 沙拉沙星单抗(2H4) | 5865 |
| 磺胺对甲氧嘧啶（SMD）单抗 | 6012 |
| 磺胺类SAS单抗 | 5905 |
