Anti-Human CD71/TFRC Recombinant Antibody|抗人CD71/TFRC重组抗体(靶标：人转铁蛋白受体1/CD71)
- 货号：RB9THY036053
- 价格：面议
- 点击：236
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, neutralization |
| 种属反应性 | Human |
| 靶标 | CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P02786 |
| 背景信息 | Transferrin receptor protein 1 (TRFC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. 1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738 2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 7481 |
| 白细胞介素6（IL-6）单克隆抗体 | 7206 |
| 肝素结合蛋白单克隆抗体 | 6623 |
| CRP单克隆抗体 | 7386 |
| 猫胰脂肪酶单克隆抗体 | 7035 |
| 马SAA单克隆抗体 | 7280 |
| 犬腺病毒单克隆抗体 | 6790 |
| 犬轮状病毒单克隆抗体 | 6832 |
| 犬血红蛋白单克隆抗体 | 7711 |
| 犬胰脂肪酶单克隆抗体 | 6631 |
| 犬松弛素单克隆抗体 | 7004 |
| 犬冠状病毒单克隆抗体 | 7054 |
| 犬瘟病毒单克隆抗体 | 6726 |
| 犬细小病毒单克隆抗体 | 7141 |
| 猫瘟病毒单克隆抗体 | 7238 |
| 猫疱疹病毒单克隆抗体 | 7038 |
| 猫杯状病毒单克隆抗体 | 7456 |
| 猫SAA单克隆抗体 | 7103 |
| 犬CRP单克隆抗体 | 7629 |
| 犬、猫IgG单克隆抗体 | 7019 |