| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG H-gamma2-4 chimerisotype G2[11aaG4]-kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 储存缓冲液 | 0.01 M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -82°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P01031 |
| 背景信息 | Complement C5 (ComplementC5) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019 4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279 5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 |
| 备注 | For research use only. |
| 产品名称 | 点击数 |
|---|---|
| CA-125单克隆抗体 | 6856 |
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| AFP单克隆抗体 | 6888 |
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| HE4单克隆抗体 | 6619 |
| 孕酮单克隆抗体 | 7200 |
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| 胎盘泌乳素单克隆抗体 | 6872 |
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| AMH单克隆抗体 | 7170 |
| 胎儿纤维链接蛋白单克隆抗体 | 6955 |
| HCG单克隆抗体 | 6832 |
| 人骨碱性磷酸酶单克隆抗体 | 6697 |
| 小分子单克隆抗体 | 6910 |
| 抗环瓜氨酸肽抗体(Anti-CCP)诊断试剂原料 | 6838 |
| 耐碳青霉烯单克隆抗体 | 6994 |
| 补体C4c单克隆抗体 | 7221 |
| 补体C3c单克隆抗体 | 6802 |