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Anti-Human ANXA1/Annexin A1 Reference Antibody|抗人ANXA1/膜联蛋白A1参照抗体(靶标:人膜联蛋白A1(研究用))

  • 货号:RB9THY216016
  • 价格:面议
  • 点击:195

产品介绍

产品参数

形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG1, kappa
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
内毒素水平< 10 EU/mg
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
储存缓冲液0.01 M PBS pH 7.4
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -87°C long term.
产品使用说明ELISA: 1:2000-1:20000
登录号P04083
背景信息

Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells.

1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544
2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549
3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660
4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504
5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678
备注For research use only.
【仅供科学研究使用】

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