当前位置：首页>产品中心>单抗/多抗>Anti-Human ErbB2/Her2 Reference Antibody|抗人ErbB2/Her2参照抗体(靶标：人受体酪氨酸蛋白激酶ERBB2/HER2(研究用))
Anti-Human ErbB2/Her2 Reference Antibody|抗人ErbB2/Her2参照抗体(靶标：人受体酪氨酸蛋白激酶ERBB2/HER2(研究用))
- 货号：RB9THY286186
- 价格：面议
- 点击：322
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | immunoglobulin (H-gamma1_L-kappa)_scFvhk-G1(h-CH2- |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 储存缓冲液 | 0.01 M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -90°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P04626 |
| 背景信息 | Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. |
| 备注 | For research use only. |
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