当前位置：首页>产品中心>单抗/多抗>Anti-Human ErbB3/Her3 Reference Antibody|抗人ErbB3/Her3参照抗体(靶标：人受体酪氨酸蛋白激酶ERBB3/HER3(研究用))
Anti-Human ErbB3/Her3 Reference Antibody|抗人ErbB3/Her3参照抗体(靶标：人受体酪氨酸蛋白激酶ERBB3/HER3(研究用))
- 货号：RB9THB116166
- 价格：面议
- 点击：323
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 储存缓冲液 | 0.01 M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -102°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P21860 |
| 背景信息 | Receptor tyrosine-protein kinase erbB-3 (ERBB3/HER3) is a ~148 kDa protein. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Kinugasa, Y. et al. (2004) Biochemical and biophysical research communications 321, 1045-9. PMID: 15358134 3. Braunstein, EM. et al. (2016) Leukemia 30, 2242-2245. PMID: 27416908 |
| 备注 | For research use only. |
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