| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1, kappa fused with NRG1 |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 储存缓冲液 | 0.01 M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -103°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P21860 |
| 背景信息 | Receptor tyrosine-protein kinase erbB-3 (ERBB3/HER3) is a ~148 kDa protein. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Kinugasa, Y. et al. (2004) Biochemical and biophysical research communications 321, 1045-9. PMID: 15358134 3. Braunstein, EM. et al. (2016) Leukemia 30, 2242-2245. PMID: 27416908 |
| 备注 | For research use only. |
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7538 |
| 人触珠蛋白单克隆抗体 | 7744 |
| 贾第鞭毛虫单克隆抗体 | 7389 |
| 阿米巴单克隆抗体 | 7938 |
| 胃蛋白酶单克隆抗体 | 7419 |
| 胃蛋白酶原II单克隆抗体 | 7652 |
| 胃蛋白酶原I单克隆抗体 | 7362 |
| 艰难梭菌毒素A单克隆抗体 | 7515 |
| 艰难梭菌毒素B单克隆抗体 | 7820 |
| 艰难梭菌GDH单克隆抗体 | 7808 |
| 诺如病毒单克隆抗体 | 7295 |
| 伤寒沙门氏菌单克隆抗体 | 7387 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6885 |
| 幽门螺杆菌单克隆抗体 | 7414 |
| 钙卫蛋白单克隆抗体 | 7178 |
| 乳铁蛋白单克隆抗体 | 7542 |
| 转铁蛋白单克隆抗体 | 7545 |
| 血红蛋白单克隆抗体 | 7253 |
| 腺病毒单克隆抗体 | 7477 |
| 轮状病毒单克隆抗体 | 7882 |