当前位置:首页>产品中心>单抗/多抗>Anti-Human CD39/ENTPD1 Reference Antibody|抗人CD39/ENTPD1参照抗体(靶标:人外核苷酸三磷酸二磷酸水解酶1/CD39(研究用))

Anti-Human CD39/ENTPD1 Reference Antibody|抗人CD39/ENTPD1参照抗体(靶标:人外核苷酸三磷酸二磷酸水解酶1/CD39(研究用))

  • 货号:RB9THW564116
  • 价格:面议
  • 点击:401
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产品介绍

产品参数

形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG1, kappa
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
内毒素水平< 10 EU/mg
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
储存缓冲液0.01 M PBS pH 7.4
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -111°C long term.
产品使用说明ELISA: 1:2000-1:20000
登录号P49961
背景信息

Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.

1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670
2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624
3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160
4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251
备注For research use only.
【仅供科学研究使用】

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