当前位置：首页>产品中心>单抗/多抗>Anti-Human CD276/B7-H3 Reference Antibody|抗人CD276/B7-H3参照抗体(靶标：人CD276分子/B7-H3(研究用))
Anti-Human CD276/B7-H3 Reference Antibody|抗人CD276/B7-H3参照抗体(靶标：人CD276分子/B7-H3(研究用))
- 货号：RB9THV612116
- 价格：面议
- 点击：326
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 储存缓冲液 | 0.01 M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -119°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | Q5ZPR3 |
| 背景信息 | CD276 antigen (B7-H3) is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. CD276 is the therapeutic target of omburtamab (clinical). |
| 备注 | For research use only. |
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