当前位置：首页>产品中心>单抗/多抗>Anti-Human CD272/BTLA Reference Antibody|抗人CD272/BTLA参照抗体(靶标：人B和T淋巴细胞衰减因子/CD272(研究用))
Anti-Human CD272/BTLA Reference Antibody|抗人CD272/BTLA参照抗体(靶标：人B和T淋巴细胞衰减因子/CD272(研究用))
- 货号：RB9THV375076
- 价格：面议
- 点击：358
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 储存缓冲液 | 0.01 M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -120°C long term. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | Q7Z6A9 |
| 背景信息 | B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. 1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776 2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006 3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026 4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044 |
| 备注 | For research use only. |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7526 |
| 人触珠蛋白单克隆抗体 | 7731 |
| 贾第鞭毛虫单克隆抗体 | 7374 |
| 阿米巴单克隆抗体 | 7920 |
| 胃蛋白酶单克隆抗体 | 7412 |
| 胃蛋白酶原II单克隆抗体 | 7620 |
| 胃蛋白酶原I单克隆抗体 | 7333 |
| 艰难梭菌毒素A单克隆抗体 | 7499 |
| 艰难梭菌毒素B单克隆抗体 | 7789 |
| 艰难梭菌GDH单克隆抗体 | 7783 |
| 诺如病毒单克隆抗体 | 7279 |
| 伤寒沙门氏菌单克隆抗体 | 7370 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6876 |
| 幽门螺杆菌单克隆抗体 | 7387 |
| 钙卫蛋白单克隆抗体 | 7153 |
| 乳铁蛋白单克隆抗体 | 7523 |
| 转铁蛋白单克隆抗体 | 7524 |
| 血红蛋白单克隆抗体 | 7240 |
| 腺病毒单克隆抗体 | 7464 |
| 轮状病毒单克隆抗体 | 7854 |