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Anti-RVFV Glycoprotein N/Gn Recombinant Antibody |抗RVFV糖蛋白N/Gn重组抗体(靶标:裂谷热病毒糖蛋白N)

  • 货号:RB9TVK101013
  • 价格:面议
  • 点击:455

产品介绍

产品参数

形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG1, kappa
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
内毒素水平Please contact with the lab for this information.
应用ELISA, Neutralization, in vivo
种属反应性Rift valley fever virus (RVFV)
靶标Envelopment polyprotein, GP, Glycoprotein G1, Glycoprotein N, Gn
储存缓冲液0.01M PBS pH 7.4
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重构方法Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输条件In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
登录号P21401
背景信息

Envelopment polyprotein (Gn) is a ~130 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins and polymerase during virus assembly.

1. Freiberg, AN. et al. (2008) Journal of virology 82, 10341-8. PMID: 18715915
2. Halldorsson, S. et al. (2018) Nature communications 9, 349. PMID: 29367607
3. Lozach, PY. et al. (2011) Cell host & microbe 10, 75-88. PMID: 21767814
4. Piper, ME. et al. (2011) PloS one 6, e18070. PMID: 21445316
备注For research use only
【仅供科学研究使用】

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