当前位置：首页>产品中心>单抗/多抗>Anti-Human CD120b/TNFRSF1B/TNFR2 Reference Antibody|抗人CD120b/TNFRSF1B/TNFR2参照抗体(靶标：人肿瘤坏死因子受体超家族成员1B/TNFR2/CD120b(研究用))
Anti-Human CD120b/TNFRSF1B/TNFR2 Reference Antibody|抗人CD120b/TNFRSF1B/TNFR2参照抗体(靶标：人肿瘤坏死因子受体超家族成员1B/TNFR2/CD120b(研究用))
- 货号：RB9THB070086
- 价格：面议
- 点击：524
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2, lambda |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | < 10 EU/mg |
| 应用 | ELISA, FACS, Functional assay |
| 种属反应性 | Human |
| 靶标 | TNF-R2, TNFR-II, p80 TNF-alpha receptor, Etanercept, TNFBR, TBP-2, TBPII, Tumor necrosis factor receptor superfamily member 1B, CD120b, p75, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNFR2, |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | P20333 |
| 背景信息 | Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFR2) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity. |
| 备注 | For research use only. |
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