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Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody|抗HHV-5/HCMV糖蛋白H/gH多克隆抗体(靶标:人巨细胞病毒包膜糖蛋白H)

  • 货号:RB9TVK665014
  • 价格:面议
  • 点击:169

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human cytomegalovirus
靶标Envelope glycoprotein H, UL75, gH
免疫原E. coli - derived recombinant HHV-5/HCMV glycoprotein H/gH (Phe298-Val605).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P12824
背景信息

Envelope glycoprotein H (gH) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2.

备注For research use only
【仅供科学研究使用】

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