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首页>产品中心>单抗/多抗>Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody|抗HHV-5/HCMV糖蛋白H/gH多克隆抗体(靶标:人巨细胞病毒包膜糖蛋白H)
Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody|抗HHV-5/HCMV糖蛋白H/gH多克隆抗体(靶标:人巨细胞病毒包膜糖蛋白H)
- 货号:RB9TVK665014
- 价格:面议
- 点击:175
产品介绍
产品参数
| 形态 | Liquid |
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| 宿主种属 | Rabbit |
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| 克隆性 | Polyclonal |
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| 抗体亚型 | IgG |
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| 纯化方式 | Purified by antigen affinity column. |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, IHC, WB |
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| 种属反应性 | Human cytomegalovirus |
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| 靶标 | Envelope glycoprotein H, UL75, gH |
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| 免疫原 | E. coli - derived recombinant HHV-5/HCMV glycoprotein H/gH (Phe298-Val605). |
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| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
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| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
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| 登录号 | P12824 |
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| 背景信息 | Envelope glycoprotein H (gH) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2. |
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| 备注 | For research use only |
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【仅供科学研究使用】
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