| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human cytomegalovirus |
| 靶标 | Envelope glycoprotein UL130, UL130 |
| 免疫原 | E. coli - derived recombinant HHV-5/HCMV UL130 (Ser26-Val214). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | F5HCP3 |
| 背景信息 | Envelope glycoprotein UL130 is a ~24 kDa protein. Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. 1. Ryckman, BJ. et al. (2008) Journal of virology 82, 60-70. PMID: 17942555 2. Nogalski, MT. et al. (2013) PLoS pathogens 9, e1003463. PMID: 23853586 3. Chandramouli, S. et al. (2017) Science immunology 2. PMID: 28783665 4. Martinez-Martin, N. et al. (2018) Cell 174, 1158-1171.e19. PMID: 30057110 |
| 备注 | For research use only |