当前位置:首页>产品中心>单抗/多抗>Anti-Hepatitis E virus/HEV ORF3 Polyclonal Antibody|抗戊型肝炎病毒/HEV ORF3多克隆抗体(靶标:戊型肝炎病毒开放阅读框3蛋白)

Anti-Hepatitis E virus/HEV ORF3 Polyclonal Antibody|抗戊型肝炎病毒/HEV ORF3多克隆抗体(靶标:戊型肝炎病毒开放阅读框3蛋白)

  • 货号:RB9TVK620054
  • 价格:面议
  • 点击:270
   一键复制产品信息 复制成功!

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Hepatitis E virus genotype 2 (HEV-2)
靶标Protein ORF3, pORF3
免疫原E. coli - derived recombinant HEV ORF3 (Met1-Arg114).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重构方法Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输条件In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q03499
背景信息

Protein ORF3 (Methyltransferase/Met) is a ~11 kDa protein. Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Also acts as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by down-regulating host TLR3 and TLR7 as well as their downstream signaling pathways. Down-regulates the phosphorylation of host IRF3 via the interaction with host SIRP-alpha, thereby inhibiting IFN-I expression.

备注For research use only
【仅供科学研究使用】

相关产品:
总计 33037 个记录,共 1652 页,当前第 3 页 | 第一页 上一页 下一页 最末页
在线客服
  • 销售热线:
  • 15898894496(同微信)
  • 我要留言
  • 周一至周五每天9:00-17:00