当前位置：首页>产品中心>单抗/多抗>Anti-Lassa virus/LASV Nucleoprotein Polyclonal Antibody|抗拉沙病毒/LASV核蛋白多克隆抗体(靶标：拉沙病毒核蛋白)
Anti-Lassa virus/LASV Nucleoprotein Polyclonal Antibody|抗拉沙病毒/LASV核蛋白多克隆抗体(靶标：拉沙病毒核蛋白)
- 货号：RB9TVK810034
- 价格：面议
- 点击：447
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Lassa virus |
| 靶标 | EC:3.1.13.-, N, Nucleocapsid protein, Nucleoprotein, Protein N |
| 免疫原 | E. coli - derived recombinant Lassa virus/LASV Nucleoprotein (Met1-Leu569). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P13699 |
| 背景信息 | Nucleoprotein is a ~62 kDa protein. Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. |
| 备注 | For research use only |
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