当前位置:首页>产品中心>单抗/多抗>Anti-Lassa virus/LASV RdRp/Protein L Polyclonal Antibody|抗拉沙病毒/LASV RdRp/蛋白L多克隆抗体(靶标:拉沙病毒RNA聚合酶大亚基)

Anti-Lassa virus/LASV RdRp/Protein L Polyclonal Antibody|抗拉沙病毒/LASV RdRp/蛋白L多克隆抗体(靶标:拉沙病毒RNA聚合酶大亚基)

  • 货号:RB9TVK810044
  • 价格:面议
  • 点击:538
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mammarenavirus lassaense, Lassa virus
靶标EC:2.7.7.48, EC:3.1.-.-, L, Large structural protein, Protein L, RNA-directed RNA polymerase L, Replicase, Transcriptase, cap-snatching endonuclease
免疫原E. coli - derived recombinant Lassa virus/LASV RdRp/Protein L (Glu2-Tyr170).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O09705
背景信息

RNA-directed RNA polymerase L (RdRp/Protein L) is a ~253 kDa protein. RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate. During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs. These short capped RNAs are then used as primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped.

备注For research use only
【仅供科学研究使用】

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