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首页>产品中心>单抗/多抗>Anti-Lassa virus/LASV RdRp/Protein L Polyclonal Antibody|抗拉沙病毒/LASV RdRp/蛋白L多克隆抗体(靶标:拉沙病毒RNA聚合酶大亚基)
Anti-Lassa virus/LASV RdRp/Protein L Polyclonal Antibody|抗拉沙病毒/LASV RdRp/蛋白L多克隆抗体(靶标:拉沙病毒RNA聚合酶大亚基)
- 货号:RB9TVK810044
- 价格:面议
- 点击:527
产品介绍
产品参数
| 形态 | Liquid |
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| 宿主种属 | Rabbit |
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| 克隆性 | Polyclonal |
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| 抗体亚型 | IgG |
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| 纯化方式 | Purified by antigen affinity column. |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, IHC, WB |
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| 种属反应性 | Mammarenavirus lassaense, Lassa virus |
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| 靶标 | EC:2.7.7.48, EC:3.1.-.-, L, Large structural protein, Protein L, RNA-directed RNA polymerase L, Replicase, Transcriptase, cap-snatching endonuclease |
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| 免疫原 | E. coli - derived recombinant Lassa virus/LASV RdRp/Protein L (Glu2-Tyr170). |
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| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
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| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
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| 登录号 | O09705 |
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| 背景信息 | RNA-directed RNA polymerase L (RdRp/Protein L) is a ~253 kDa protein. RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate. During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs. These short capped RNAs are then used as primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped. |
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| 备注 | For research use only |
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【仅供科学研究使用】
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