| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Lassa virus |
| 靶标 | Protein Z, RING finger protein Z, Z, Zinc-binding protein |
| 免疫原 | E. coli - derived recombinant Lassa virus/LASV Protein Z (Gly2-Pro99). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O73557 |
| 背景信息 | RING finger protein Z is a ~10 kDa protein. Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. 1. Strecker, T. et al. (2003) Journal of virology 77, 10700-5. PMID: 12970458 2. Cornu, TI. et al. (2004) Journal of virology 78, 2979-83. PMID: 14990716 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| CA-125单克隆抗体 | 7048 |
| PSA单克隆抗体 | 7115 |
| AFP单克隆抗体 | 7108 |
| CA-724单克隆抗体 | 7003 |
| CA-199单克隆抗体 | 6933 |
| HE4单克隆抗体 | 6803 |
| 孕酮单克隆抗体 | 7416 |
| 人胎球蛋白A(Fetuin A)单克隆抗体 | 7147 |
| 胎盘泌乳素单克隆抗体 | 7066 |
| 泌乳素单克隆抗体 | 6750 |
| SP-10单克隆抗体 | 6979 |
| AMH单克隆抗体 | 7295 |
| 胎儿纤维链接蛋白单克隆抗体 | 7121 |
| HCG单克隆抗体 | 7032 |
| 人骨碱性磷酸酶单克隆抗体 | 6812 |
| 小分子单克隆抗体 | 7151 |
| 抗环瓜氨酸肽抗体(Anti-CCP)诊断试剂原料 | 6992 |
| 耐碳青霉烯单克隆抗体 | 7137 |
| 补体C4c单克隆抗体 | 7337 |
| 补体C3c单克隆抗体 | 6863 |