当前位置：首页>产品中心>单抗/多抗>Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody|抗结核分枝杆菌异柠檬酸裂解酶/ICL多克隆抗体(靶标：结核分枝杆菌异柠檬酸裂解酶)
Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody|抗结核分枝杆菌异柠檬酸裂解酶/ICL多克隆抗体(靶标：结核分枝杆菌异柠檬酸裂解酶)
- 货号：RB9TJN930024
- 价格：面议
- 点击：436
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mycobacterium tuberculosis, Mycobacterium bovis |
| 靶标 | EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl |
| 免疫原 | E. coli - derived recombinant Mycobacterium tuberculosis Isocitrate lyase/ICL (Met1-His428). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P9WKK7 |
| 背景信息 | Isocitrate lyase (ICL) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). 1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251 2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599 3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086 4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272 |
| 备注 | For research use only |
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