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Anti-HBoV1 Minor capsid protein VP1 Polyclonal Antibody|抗HBoV1次要衣壳蛋白VP1多克隆抗体(靶标:人博卡病毒1型次要衣壳蛋白VP1)

  • 货号:RB9TVK140014
  • 价格:面议
  • 点击:369

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Primate bocaparvovirus 1
靶标EC:3.1.1.4, Minor capsid protein VP1, VP1
免疫原E. coli - derived recombinant HBoV1 Minor capsid protein VP1 (Lys181-Gly290).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q3YPH4
背景信息

Minor capsid protein VP1 is a ~75 kDa protein. Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1 (Probable). The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA (Probable). Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.

1. Mietzsch, M. et al. (2017) Journal of virology 91. PMID: 28331084
备注For research use only
【仅供科学研究使用】

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