当前位置:首页>产品中心>单抗/多抗>Anti-Rabies virus Phosphoprotein Polyclonal Antibody|抗狂犬病病毒磷蛋白多克隆抗体(靶标:狂犬病病毒磷蛋白)

Anti-Rabies virus Phosphoprotein Polyclonal Antibody|抗狂犬病病毒磷蛋白多克隆抗体(靶标:狂犬病病毒磷蛋白)

  • 货号:RB9TVK139014
  • 价格:面议
  • 点击:488

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rabies virus
靶标P, Phosphoprotein, Protein M1, Protein P
免疫原E. coli - derived recombinant Rabies virus Phosphoprotein (Met69-Cys297).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P22363
背景信息

Phosphoprotein is a ~33 kDa protein. Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body. Inhibits interferon induction pathways by interacting with host TBK1 and preventing the formation of dynamic cytoplasmic condensates that have liquid properties and that are essential for interferon production.

备注For research use only
【仅供科学研究使用】

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