| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yeast |
| 靶标 | EC:1.11.1.24, GPX3, GPx 3, Glutathione peroxidase homolog 3, Glutathione peroxidase-like peroxiredoxin HYR1, HYR1, Hydrogen peroxide resistance protein 1, ORP1, Oxidant receptor peroxidase 1, PHGPx3, |
| 免疫原 | E. coli - derived recombinant Yeast HYR1/GPX3 (Met1-Glu163). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P40581 |
| 背景信息 | Glutathione peroxidase-like peroxiredoxin HYR1 (GPX3) is a ~18 kDa protein. Involved in oxidative stress response and redox homeostasis. Functions as a sensor and transducer of hydroperoxide stress. In response to hydroperoxide stress it oxidizes (activates) the transcription activator YAP1, which is involved in transcription activation of genes of the oxidative stress response pathway. May also play a direct role in hydroperoxide scavenging, being the most active of three closely related S.cerevisiae peroxiredoxins (GPX1, GPX2, and HYR1/GPX3) with respect to peroxide and lipid hydroperoxide reduction. The three enzymes are not required for the glutaredoxin-mediated antioxidant function. |
| 备注 | For research use only |