| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Staphylococcus aureus |
| 靶标 | EC:3.4.22.70, Sortase A, Surface protein sorting A, srtA |
| 免疫原 | E. coli - derived recombinant Staphylococcus aureus Sortase A/SrtA (Gln60-Lys206). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q2FV99 |
| 背景信息 | Sortase A (SrtA) is a ~23 kDa protein. Transpeptidase that anchors surface proteins to the cell wall. Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall. This sortase recognizes a Leu-Pro-x-Thr-Gly (LPXTG) motif, which is cleaved by the sortase between the threonine and glycine residues. Utilizes lipid II as the peptidoglycan substrate for the sorting reaction. 1. Mazmanian, SK. et al. (1999) Science (New York, N.Y.) 285, 760-3. PMID: 10427003 2. Ton-That, H. et al. (1999) The Journal of biological chemistry 274, 24316-20. PMID: 10446208 3. Ton-That, H. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 12424-9. PMID: 10535938 4. Ton-That, H. et al. (2002) The Journal of biological chemistry 277, 7447-52. PMID: 11714722 5. Kruger, RG. et al. (2004) Biochemistry 43, 1541-51. PMID: 14769030 6. Marraffini, LA. et al. (2004) The Journal of biological chemistry 279, 37763-70. PMID: 15247224 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| Trx鼠单抗标签 | 7845 |
| BrdU单抗 | 7874 |
| HRP-BrdU单抗 | 7608 |
| GAPDH 鼠单抗 | 7527 |
| HRP-GAPDH 鼠单抗 | 7546 |
| PCNA单抗 | 8025 |
| α-tubulin 鼠单抗 | 7486 |
| β-tubulin 鼠单抗 | 7988 |
| HRP-β-tubulin 鼠单抗 | 7756 |
| β-Actin 鼠单抗 | 7907 |
| HRP-β-Actin 鼠单抗 | 7507 |
| Histone H3鼠单抗 | 7632 |
| 糖基化血红蛋白单抗 | 7929 |
| 糖基化血红蛋白抗体 | 7840 |
| C肽鼠单抗 | 7142 |
| 胰岛素鼠单抗 | 7667 |
| 胃蛋白酶原II鼠单抗 | 7765 |
| 鼠抗人胃泌素17单抗 | 7567 |
| 心肌钙蛋白鼠单抗(CTNI抗体) | 7675 |
| 肌红蛋白鼠单抗 | 7789 |