当前位置：首页>产品中心>单抗/多抗>Anti-Staphylococcus aureus Sortase A/SrtA Polyclonal Antibody|抗金黄色葡萄球菌分选酶A/SrtA多克隆抗体(靶标：金黄色葡萄球菌分选酶A)
Anti-Staphylococcus aureus Sortase A/SrtA Polyclonal Antibody|抗金黄色葡萄球菌分选酶A/SrtA多克隆抗体(靶标：金黄色葡萄球菌分选酶A)
- 货号：RB9TJN051024
- 价格：面议
- 点击：257
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Staphylococcus aureus |
| 靶标 | EC:3.4.22.70, Sortase A, Surface protein sorting A, srtA |
| 免疫原 | E. coli - derived recombinant Staphylococcus aureus Sortase A/SrtA (Gln60-Lys206). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q2FV99 |
| 背景信息 | Sortase A (SrtA) is a ~23 kDa protein. Transpeptidase that anchors surface proteins to the cell wall. Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall. This sortase recognizes a Leu-Pro-x-Thr-Gly (LPXTG) motif, which is cleaved by the sortase between the threonine and glycine residues. Utilizes lipid II as the peptidoglycan substrate for the sorting reaction. 1. Mazmanian, SK. et al. (1999) Science (New York, N.Y.) 285, 760-3. PMID: 10427003 2. Ton-That, H. et al. (1999) The Journal of biological chemistry 274, 24316-20. PMID: 10446208 3. Ton-That, H. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 12424-9. PMID: 10535938 4. Ton-That, H. et al. (2002) The Journal of biological chemistry 277, 7447-52. PMID: 11714722 5. Kruger, RG. et al. (2004) Biochemistry 43, 1541-51. PMID: 14769030 6. Marraffini, LA. et al. (2004) The Journal of biological chemistry 279, 37763-70. PMID: 15247224 |
| 备注 | For research use only |
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