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Anti-Pig CD163 Polyclonal Antibody|抗猪CD163多克隆抗体(靶标:猪CD163分子)
- 货号:RB9TSV831014
- 价格:面议
- 点击:308
产品介绍
产品参数
| 形态 | Liquid |
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| 宿主种属 | Rabbit |
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| 克隆性 | Polyclonal |
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| 抗体亚型 | IgG |
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| 纯化方式 | Purified by antigen affinity column. |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, IHC, WB |
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| 种属反应性 | Human |
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| 靶标 | CD163, M130, Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163 |
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| 免疫原 | E. coli - derived recombinant Pig CD163 (Arg475-Ser577). |
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| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
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| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
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| 登录号 | Q2VL90 |
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| 背景信息 | Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV). |
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| 备注 | For research use only |
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【仅供科学研究使用】
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