| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pseudotuberculosis serotype I, Yersinia enterocolitica |
| 靶标 | T3SS translocon protein SctE, Translocator YopB, Type 3 secretion system translocon protein SctE, Yersinia outer protein B, sctE, yopB |
| 免疫原 | E. coli - derived recombinant Yersinia enterocolitica sctE/YopB (Gly246-Val401). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P37131 |
| 背景信息 | Type 3 secretion system translocon protein SctE (YopB) is a ~41 kDa protein. Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. YopB/SctE and YopD/SctB are inserted into the host membrane where they form a pore and allow the translocation of effector proteins into the cytosol of target cells. Is an essential virulence determinant. Required for YopE translocation. 1. Neyt, C. et al. (1999) Molecular microbiology 33, 971-81. PMID: 10476031 2. Tardy, F. et al. (1999) The EMBO journal 18, 6793-9. PMID: 10581252 3. Lee, VT. et al. (1999) Molecular microbiology 31, 1619-29. PMID: 10209737 4. Nordfelth, R. et al. (2001) Infection and immunity 69, 3516-8. PMID: 11292787 |
| 备注 | For research use only |