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Anti-BPV-1 VP3 Polyclonal Antibody|抗BPV-1 VP3多克隆抗体(靶标:牛乳头瘤病毒1型衣壳蛋白VP3)

  • 货号:RB9TVK809014
  • 价格:面议
  • 点击:496

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Bovine parvovirus 1
靶标EC:3.1.1.4, Minor capsid protein VP1
免疫原E. coli - derived recombinant BPV-1 VP3 (Gly178-Leu673).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P07297
背景信息

Minor capsid protein VP1 (VP3) is a ~74 kDa protein. Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.

备注For research use only
【仅供科学研究使用】

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