| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Crimean-Congo hemorrhagic fever virus |
| 靶标 | 15 kDa protein, 37 kDa protein, 75 kDa protein, Envelopment polyprotein, GP, GP38, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Gn, M polyprotein, Mucin-like variable region, |
| 免疫原 | E. coli - derived recombinant CCHFV GP38 (Asn248-Ser515). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8JSZ3 |
| 背景信息 | Envelopment polyprotein (GP38) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state. 1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887 2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291 3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197 |
| 备注 | For research use only |