| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | 4-Cys CXCL17, 6-Cys CXCL17, C-X-C motif chemokine 17, CXCL17, DMC, Dendritic cell and monocyte chemokine-like protein, VCC1, VEGF coregulated chemokine 1 |
| 免疫原 | E. coli - derived recombinant Human CXCL17/DMC/VCC1 (Ser22-Leu119). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q6UXB2 |
| 背景信息 | C-X-C motif chemokine 17 (CXCL17/DMC) is a ~13 kDa protein. Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells, and which is involved in immune regulation and lymphocyte trafficking. Activates the C-X-C chemokine receptor GPR25. Plays a key role in lymphocyte homing by activating the receptor GPR25 on lymphocytes, mediating lymphocyte recruitment into the respiratory, upper gastrointestinal, biliary and genito-urinary tracts. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. 1. Pisabarro, MT. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2069-73. PMID: 16455961 2. Lee, WY. et al. (2013) American journal of physiology. Endocrinology and metabolism 304, E32-40. PMID: 23115081 3. Ocón, B. et al. (2024) Nature 635, 736-745. PMID: 39293486 4. Hu, WF. et al. (2025) The FEBS journal 292, 5998-6015. PMID: 40279398 5. Weinstein, EJ. et al. (2006) Biochemical and biophysical research communications 350, 74-81. PMID: 16989774 |
| 备注 | For research use only |