| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Connexin-50, Cx50, GJA8, Gap junction alpha-8 protein, Lens fiber protein MP70 |
| 免疫原 | E. coli - derived recombinant Human GJA8 (Gly225-Val433). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P48165 |
| 背景信息 | Gap junction alpha-8 protein (GJA8) is a ~48 kDa protein. Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. 1. Arora, A. et al. (2008) Journal of medical genetics 45, 155-60. PMID: 18006672 2. Graw, J. et al. (2009) Molecular vision 15, 1881-5. PMID: 19756179 |
| 备注 | For research use only |