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Anti-Human GJA8 Polyclonal Antibody|抗人GJA8多克隆抗体(靶标:人间隙连接蛋白α8/连接蛋白50)

  • 货号:RB9THD640014
  • 价格:面议
  • 点击:389
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标Connexin-50, Cx50, GJA8, Gap junction alpha-8 protein, Lens fiber protein MP70
免疫原E. coli - derived recombinant Human GJA8 (Gly225-Val433).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P48165
背景信息

Gap junction alpha-8 protein (GJA8) is a ~48 kDa protein. Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.

1. Arora, A. et al. (2008) Journal of medical genetics 45, 155-60. PMID: 18006672
2. Graw, J. et al. (2009) Molecular vision 15, 1881-5. PMID: 19756179
备注For research use only
【仅供科学研究使用】

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