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Anti-Human GFM2 Polyclonal Antibody|抗人GFM2多克隆抗体(靶标:人G延伸因子线粒体2)

  • 货号:RB9THD643014
  • 价格:面议
  • 点击:513

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标EC:3.6.5.-, EF-G2mt, EFG2, Elongation factor G 2, mitochondrial, Elongation factor G2, GFM2, RRF2mt, Ribosome-releasing factor 2, mitochondrial, hEFG2, mEF-G 2
免疫原E. coli - derived recombinant Human GFM2 (Ala461-Thr779).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q969S9
背景信息

Ribosome-releasing factor 2, mitochondrial (GFM2) is a ~86 kDa protein. Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.

1. Tsuboi, M. et al. (2009) Molecular cell 35, 502-10. PMID: 19716793
2. Kummer, E. et al. (2021) Molecular cell 81, 2566-2582.e6. PMID: 33878294
备注For research use only
【仅供科学研究使用】

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