Anti-Human POLG2 Polyclonal Antibody|抗人POLG2多克隆抗体(靶标：人DNA聚合酶γ辅助亚基)
- 货号：RB9THD645014
- 价格：面议
- 点击：227
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | DNA polymerase gamma accessory 55 kDa subunit, DNA polymerase subunit gamma-2, MTPOLB, Mitochondrial DNA polymerase accessory subunit, MtPolB, POLG2, PolG-beta, p55 |
| 免疫原 | E. coli - derived recombinant Human POLG2 (Arg182-Val485). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UHN1 |
| 背景信息 | DNA polymerase subunit gamma-2 (POLG2) is a ~54 kDa protein. Accessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by increasing its interactions with the DNA template. Suppresses POLG exonucleolytic proofreading especially toward homopolymeric templates bearing mismatched termini. Binds to single-stranded DNA. |
| 备注 | For research use only |
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