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Anti-Human TRABD2A Polyclonal Antibody|抗人TRABD2A多克隆抗体(靶标:人TraB结构域含蛋白2A)

  • 货号:RB9THA378024
  • 价格:面议
  • 点击:332
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标C2orf89, EC:3.4.-.-, Metalloprotease TIKI1, TIKI1, TRAB domain-containing protein 2A, TRABD2A
免疫原E. coli - derived recombinant Human TRABD2A (Ala20-His360).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q86V40
背景信息

Metalloprotease TIKI1 (TRABD2A) is a ~57 kDa protein. Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

备注For research use only
【仅供科学研究使用】

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