| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | FMN2, Formin-2 |
| 免疫原 | E. coli - derived recombinant Human FMN2 (Ser1361-Thr1722). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9NZ56 |
| 背景信息 | Formin-2 (FMN2) is a ~180 kDa protein. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. 1. Vizcarra, CL. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 11884-9. PMID: 21730168 2. Peng, KW. et al. (2012) Biochimica et biophysica acta 1820, 469-81. PMID: 22330775 3. Yamada, K. et al. (2013) Molecular cell 49, 922-33. PMID: 23375502 4. Belin, BJ. et al. (2015) eLife 4, e07735. PMID: 26287480 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6363 |
| 多菌灵/阿苯达唑二合一单抗 | 6453 |
| 三氯噻嗪单抗 | 6545 |
| 吡唑醚菌酯单抗 | 6794 |
| 烯酰吗啉单抗 | 6648 |
| 抑霉唑单抗 | 6307 |
| 恶醚唑(苯醚甲环唑)单抗 | 6471 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6497 |
| 辛硫磷单抗 | 6585 |
| 多效唑单抗 | 6472 |
| 对硫磷单抗 | 6669 |
| 丙溴磷单抗 | 6719 |
| 戊唑醇单抗 | 6728 |
| 莠去津单抗 | 6576 |
| 灭蝇胺单抗 | 6252 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6530 |
| 2.4-二氯苯氧乙酸单抗 | 6369 |
| 甲基对硫磷单抗 | 6435 |
| 左旋咪唑单抗 | 6396 |
| 三唑磷单抗 | 6481 |