Anti-Human CRAT Polyclonal Antibody|抗人CRAT多克隆抗体(靶标：人肉碱O-乙酰转移酶)
- 货号：RB9THD657014
- 价格：面议
- 点击：404
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | CAT, CAT1, CRAT, Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CrAT, EC:2.3.1.137, EC:2.3.1.7 |
| 免疫原 | E. coli - derived recombinant Human CRAT (His31-Glu297). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P43155 |
| 背景信息 | Carnitine O-acetyltransferase (CRAT) is a ~70 kDa protein. Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates. 1. Govindasamy, L. et al. (2004) Journal of structural biology 146, 416-24. PMID: 15099582 2. Drecourt, A. et al. (2018) American journal of human genetics 102, 266-277. PMID: 29395073 3. Violante, S. et al. (2013) Biochimica et biophysica acta 1832, 773-9. PMID: 23485643 |
| 备注 | For research use only |
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