| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Amiloride-sensitive sodium channel subunit delta, DNACH, Delta-ENaC, Delta-NaCH, ENaCD, Epithelial Na(+) channel subunit delta, Epithelial sodium channel subunit delta, Nonvoltage-gated sodium channel |
| 免疫原 | E. coli - derived recombinant Human SCNN1D (Arg277-Tyr683). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P51172 |
| 背景信息 | Epithelial sodium channel subunit delta (SCNN1D) is a ~87 kDa protein. Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels. 1. Ji, HL. et al. (2006) The Journal of biological chemistry 281, 8233-41. PMID: 16423824 2. Bangel-Ruland, N. et al. (2010) American journal of respiratory cell and molecular biology 42, 498-505. PMID: 19520916 3. Zhao, RZ. et al. (2012) American journal of physiology. Lung cellular and molecular physiology 302, L1262-72. PMID: 22505667 4. Waldmann, R. et al. (1995) The Journal of biological chemistry 270, 27411-4. PMID: 7499195 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6422 |
| 多菌灵/阿苯达唑二合一单抗 | 6551 |
| 三氯噻嗪单抗 | 6611 |
| 吡唑醚菌酯单抗 | 6949 |
| 烯酰吗啉单抗 | 6792 |
| 抑霉唑单抗 | 6429 |
| 恶醚唑(苯醚甲环唑)单抗 | 6595 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6545 |
| 辛硫磷单抗 | 6654 |
| 多效唑单抗 | 6588 |
| 对硫磷单抗 | 6831 |
| 丙溴磷单抗 | 6818 |
| 戊唑醇单抗 | 6818 |
| 莠去津单抗 | 6670 |
| 灭蝇胺单抗 | 6387 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6642 |
| 2.4-二氯苯氧乙酸单抗 | 6468 |
| 甲基对硫磷单抗 | 6535 |
| 左旋咪唑单抗 | 6524 |
| 三唑磷单抗 | 6575 |