| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | C20orf155, CLS, CLS1, CRLS1, Cardiolipin synthase (CMP-forming), EC:2.7.8.41, Protein GCD10 homolog |
| 免疫原 | E. coli - derived recombinant Human CRLS1 (Leu2-Thr108). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UJA2 |
| 背景信息 | Cardiolipin synthase (CMP-forming) (CRLS1) is a ~32 kDa protein. Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. 1. Lu, B. et al. (2006) Journal of lipid research 47, 1140-5. PMID: 16547353 2. Houtkooper, RH. et al. (2006) FEBS letters 580, 3059-64. PMID: 16678169 3. Chen, D. et al. (2006) The Biochemical journal 398, 169-76. PMID: 16716149 4. Lee, RG. et al. (2022) Human molecular genetics 31, 3597-3612. PMID: 35147173 |
| 备注 | For research use only |